I had a problem with the Altera USB Blaster programmer.
When I connected the programmer to Windows 10 (64-bit), I received a message about an unrecognized USB device.
To solve this problem you must disable driver signature enforcement on Windows 10.
After that, select the option to update the driver and indicate the folder with the drivers installed with the software. I had drivers downloaded along with Quartus II 10.0 Web Edition.After installation, the programmer should be recognized.